Simple exploration of 101691-65-0

The synthetic route of 101691-65-0 has been constantly updated, and we look forward to future research findings.

101691-65-0, (Tetrahydro-2H-pyran-4-yl)methyl 4-methylbenzenesulfonate is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Reference Example 4: Synthesis of 7-[4-(tetrahydropyran-4-ylmethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine 7-(4-hydroxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (the compound obtained in Reference Example 3; 295 mg) was dissolved in N,N-dimethylformamide (8 ml). Thereafter, tetrahydropyran-4-ylmethyl p-toluenesulfonate (460 mg) and cesium carbonate (556 mg) were added to the obtained solution, and the obtained mixture was stirred at 90C overnight. After the reaction solution was cooled to a room temperature, distilled water (18 ml) was added thereto. The generated precipitate was collected by filtration, and the obtained product was then washed by successive suspension in a 20% ethanol solution, ethanol, and acetone to obtain the captioned compound (310 mg).

The synthetic route of 101691-65-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; NIPPON KAYAKU KABUSHIKI KAISHA; EP1630165; (2006); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics