Downstream synthetic route of 1768-64-5

1768-64-5 4-Chlorotetrahydropyran 137202, aTetrahydropyrans compound, is more and more widely used in various.

1768-64-5, 4-Chlorotetrahydropyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

It was added 18.0 parts of ethanol 90 parts of the compound represented by formula (I-7-a), and stirred for 1 hour at 23 C. To the resulting mixed solution, after addition of 4.33 parts of sodium hydroxide, 23 After stirring for 1 hour at C, over 30 minutes compound 13.05 parts of the formula (I-7-b) It dropped, and 25 hours reflux and stirred at 75 C. The resulting reaction mass was concentrated, added to 90 parts of chloroform and 30 parts of ion exchange water and stirred for 30 min at 23 C, the organic layer was removed by liquid separation. This operation was repeated five times. The recovered organic layer was filtered and concentrated the filtrate to give the compound 18.97 parts of the formula (I-7-c).

1768-64-5 4-Chlorotetrahydropyran 137202, aTetrahydropyrans compound, is more and more widely used in various.

Reference£º
Patent; SUMITOMO CHEMICAL COMPANY LIMITED; ADACHI, YUKAKO; YAMAMOTO, SATOSHI; ICHIKAWA, KOJI; (81 pag.)JP2015/27994; (2015); A;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics