Simple exploration of 1194-16-7

The synthetic route of 1194-16-7 has been constantly updated, and we look forward to future research findings.

1194-16-7, 2,2-Dimethyltetrahydropyran-4-one is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,1194-16-7

To a solution of 2,2-dimethyltetrahydro- 4H-pyran-4-one (1.0 g, 7.8 mmol, 1.0 eq) in toluene (10 mL) was added morpholine (1.0 g,11.7 mmol, 1.0 mL, 1.5 eq) and PTSA (134 mg, 780 imol, 0.1 eq). The mixture was stirred at110C for 12 hours. The reaction mixture was concentrated under reduced pressure to remove solvent to give 1.3 g of cmde compound I-i as a yellow oil, which was used in the next step without further purification.

The synthetic route of 1194-16-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; AQUINNAH PHARMACEUTICALS, INC.; BURNETT, Duane, A.; VACCA, Joseph, P.; (310 pag.)WO2018/119395; (2018); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics