1194-16-7, 2,2-Dimethyltetrahydropyran-4-one is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
In a 2 L round bottomed flask, 2,2-dimethyldihydro-2H-pyran-4(3H)-one (10.4 g, 0.08 mol) was dissolved in water (500 mL) along with sodium metabisulfite (7.7 g, 0.04mol). The mixture was allowed to stir at rt for 1.5 h, then benzylpiperazine (14.2 g,0.08 mol) was added. The mixture was stirred for 2 h and potassium cyanide (8.42 g,0.13 mol) was added to the reaction mixture. After stirring at rt for 2 days the solidformed was filtered and dried, to give the title compound as a white solid (15.4 g, yield61%). HPLC-MS (Method A): Ret, 1.98 mm; ESl-MS m/z, 314.1 (M+1)., 1194-16-7
1194-16-7 2,2-Dimethyltetrahydropyran-4-one 1738159, aTetrahydropyrans compound, is more and more widely used in various fields.
Reference£º
Patent; LABORATORIOS DEL DR. ESTEVE, S.A.; GARCIA-LOPEZ, Monica; ALMANSA-ROSALES, Carmen; LLORENTE-FERNANDEZ, Ana Virginia; CHRISTMANN, Ute; RODRIGUEZ ESCRICH, Sergio; (355 pag.)WO2017/198339; (2017); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics