Simple exploration of 4677-20-7

4677-20-7 4-(2-Bromoethyl)tetrahydropyran 22637012, aTetrahydropyrans compound, is more and more widely used in various fields.

4677-20-7, 4-(2-Bromoethyl)tetrahydropyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,4677-20-7

f) To a solution of 5-chloro-2-hydroxybenzaldehyde 162 mg (1 .0 mmol) in DMF (2 ml_), 172 mg of K2C03 (1 .2 mmol) and 4-(2-bromoethyl)tetrahydro-2H-pyran (200 mg, 1 .0 mmol) were added. Reaction was stirred at 405C overnight. Then, it was allowed to cool to room temperature. Water was added and a white precipitated appeared. The mixture was extracted with EtAcO (x3), and the organic phases combined and washed with a 10% solution of NaCI in water. It was dried with anhydrous Na2S04, filtered and the solvent evaporated to obtain 5-chloro-2-(2- (tetrahydro-2H-pyran-4-yl)ethoxy)benzaldehyde (220 mg, 80%).

4677-20-7 4-(2-Bromoethyl)tetrahydropyran 22637012, aTetrahydropyrans compound, is more and more widely used in various fields.

Reference£º
Patent; LABORATORIOS DEL DR. ESTEVE, S.A.; DRACONIS PHARMA, S.L.; ALMIRALL, S.A.; TORRENS JOVER, Andoni; MERCE VIDAL, Ramon; CALDENTEY FRONTERA, Francesc Xavier; RODRIGUEZ GARRIDO, Antonio, David; CARCELLER GONZALEZ, Elena; SALAS SOLANA, Jordi; WO2013/37960; (2013); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics