With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1194-16-7,2,2-Dimethyltetrahydropyran-4-one,as a common compound, the synthetic route is as follows.
-BuLi (26.3 ml, 1.6 M in hexane, 42 mmol) was added dropwise to a solution of 4- bromo-toluene (7.70 g, 45 mmol) in THF (100 ml) at -78 C under N2. The resulting mixture was stirred at -78 C for 30 min and a solution of tetrahydro-2,2-dimethyl-4H- pyran-4
1194-16-7, The synthetic route of 1194-16-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; TREVENA, INC.; VIOLIN, Jonathan D.; SOERGEL, David G.; (177 pag.)WO2017/106547; (2017); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics