With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.61363-56-2,2H-Pyran-3,5(4H,6H)-dione,as a common compound, the synthetic route is as follows.
61363-56-2, 1L four-necked bottle, under nitrogen atmosphere,Compound II (32.00 g, 0.28 mol, 1.0 e.q.) was dissolved in THF (300 mL).Add ammonium carbonate (80.71 g, 0.84 mol, 3.0 e.q.),Warmed to reflux and stirred for 8 h.TLC test showed that the raw materials were reacted.The reaction liquid was purified by sand column chromatography to obtain Compound III as a yellow solid 20.0 g.The yield was 63.3%.
The synthetic route of 61363-56-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Nanjing Yaoshi Technology Co., Ltd.; Nanjing Furunkaide Bio-pharmaceutical Co., Ltd.; Li Jilong; Qi Lei; Fei Qinlong; Li Hui; (15 pag.)CN108395421; (2018); A;,
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