With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.110238-91-0,Methyl tetrahydro-2H-pyran-4-carboxylate,as a common compound, the synthetic route is as follows.
Preparation 110; Tetrahydro-pyran-4-carboxylic acid amide; In a 5L flask, charge methyltetrahydropyran-4-carboxylate (500ml, 3. 75mol) and concentrated ammonium hydroxide (1.3L) and stir the reaction at room temperature for 48 hours. Filter the reaction and dry the white solid in a vacuum oven at 60¡ãC overnight. to obtained 36.33g white solid of the title compound., 110238-91-0
As the paragraph descriping shows that 110238-91-0 is playing an increasingly important role.
Reference£º
Patent; ELI LILLY AND COMPANY; WO2005/66126; (2005); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics