83-87-4, (3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,83-87-4
In a 50 mL round bottom flask, add compound 1a (2.0 g, 5.13 mmol). Dissolve it in anhydrous dichloromethane (5 mL), subsequently, a 33% hydrobromic acid in acetic acid solution (2.5 mL) was slowly added dropwise, and reacted at room temperature for 2 h. After the reaction, the reaction solution was poured into a separatory funnel and 100 mL of dichloromethane was added. The organic phase was washed with water. After extraction, the organic phase was washed with an aqueous sodium hydrogen carbonate solution. Until no bubbles are generated, and finally washed with saturated brine, the organic phase was dried over anhydrous sodium sulfate. After removing the sodium sulfate solid by filtration, the solvent was distilled off under reduced pressure, The crude product was purified by silica gel column chromatography (petroleum ether: ethyl acetate = 4: 1),1b (1.81 g) was obtained as a white flaky solid.Yield: 85.4%
As the paragraph descriping shows that 83-87-4 is playing an increasingly important role.
Reference£º
Patent; Longkou Joint Chemical Co., Ltd.; Li Xiumei; Gao Qingzhi; Ji Wei; Wang He; Wang Jian; (32 pag.)CN107602649; (2019); B;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics