33821-94-2, 2-(3-Bromopropoxy)tetrahydro-2H-pyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate Compound 2 Compound 2 (8.2 g, 31.9 MMOL) was dissolved in THF (200 mL) and cooled TO-78C. LHMDS (1 M in THF, 33.5 MMOL) was added and the content stirred AT-78C for 10 min before being transferred to a solution of 2- (3- bromopropoxy) -tetrahydro-2H-pyran (6.48 mL, 38.29 MMOL) at r. t via canula. The reaction was completed in 4 hrs and solvents were removed under reduced pressure, residue redissolved in ethyl acetate and washed with 1: 1 brine: H20, dried, filtrated and concentrated. FCC with hexane: EtOAc (5: 1 to 4: 1) afford 7.4 g of the intermediate product 3 as light yellow oil., 33821-94-2
As the paragraph descriping shows that 33821-94-2 is playing an increasingly important role.
Reference£º
Patent; SMITHKLINE BEECHAM CORPORATION; WO2004/55016; (2004); A1;,
Tetrahydropyran – Wikipedia
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