Some scientific research about Tetrahydropyran-4-carbaldehyde

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The discovery of MK-4256, a potent SSTR3 antagonist as a potential treatment of type 2 diabetes

A structure-activity relationship study of the imidazolyl-beta- tetrahydrocarboline series identified MK-4256 as a potent, selective SSTR3 antagonist, which demonstrated superior efficacy in a mouse oGTT model. MK-4256 reduced glucose excursion in a dose-dependent fashion with maximal efficacy achieved at doses as low as 0.03 mg/kg po. As compared with glipizide, MK-4256 showed a minimal hypoglycemia risk in mice.

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Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics