In an article, published in an article, once mentioned the application of 61363-56-2, Name is 2H-Pyran-3,5(4H,6H)-dione,molecular formula is C5H6O3, is a conventional compound. this article was the specific content is as follows.Quality Control of: 2H-Pyran-3,5(4H,6H)-dione
Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation
Phosphatidylinositol-3-kinase alpha (PI3Kalpha) is a therapeutic target of high interest in anticancer drug research. On the basis of a binding model rationalizing the high selectivity and potency of a particular series of 2-aminothiazole compounds in inhibiting PI3Kalpha, a medicinal chemistry program has led to the discovery of the clinical candidate NVP-BYL719.
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Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics