Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn¡¯t involve a screen. 40191-32-0, C6H9ClO2. A document type is Article, introducing its new discovery., name: Tetrahydro-2H-pyran-4-carbonyl chloride
Modular synthesis of 3,6-disubstituted-1,2,4-triazines via the cyclodehydration of beta-keto- N -acylsulfonamides with hydrazine salts
A straightforward method for preparing 3,6-disubstituted-1,2,4-triazines through a redox-efficient cyclodehydration of beta-keto-N-acylsulfonamides with hydrazine salts is described. Two approaches for synthesizing the requisite beta-keto-N-acylsulfonamides are presented, which allow for the late stage incorporation of either the C3 or C6 substituent in a flexible manner from acid chlorides or alpha-bromoketones, respectively. The scope of this methodology includes primary and secondary sp3-linked substituents at both the C3 and C6 positions, and the mild reaction conditions tolerate a variety of sensitive functionalities.
Interested yet? Keep reading other articles of 40191-32-0!, name: Tetrahydro-2H-pyran-4-carbonyl chloride
Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics