Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 585-88-6, Name is Maltitol, molecular formula is C12H24O11, belongs to Tetrahydropyrans compound. In a document, author is Hegarty, Eimear, introduce the new discover, Recommanded Product: Maltitol.
Implementation of Biocatalysis in Continuous Flow for the Synthesis of Small Cyclic Amines
Significant progress has been made in establishing transaminases as robust biocatalysts for the green and scalable synthesis of a diverse range of chiral amines.([1]) However, very few examples on the amination of small cyclic ketones have been reported.([2]) Cyclic ketones are particularly challenging for transaminase enzymes because they do not display the well-defined small and large substituent areas that are characteristic for the biocatalytic mechanism. In this work, we exploited the broad substrate scope of the (S)-selective transaminase from Halomonas elongate (HeWT) to develop an efficient biocatalytic system in continuous flow to generate a range of small cyclic amines which feature very often in pharmaceuticals and agrochemicals.([3]) Tetrahydrofuran-3-one and other challenging prochiral ketones were rapidly (5-45 min) transformed to their corresponding amines with excellent molar conversion (94-99%) and moderate to excellent ee.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 585-88-6. Recommanded Product: Maltitol.
Reference:
Tetrahydropyran – Wikipedia,
,Tetrahydropyran – an overview | ScienceDirect Topics