The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.499-40-1, Name is (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal, molecular formula is C12H22O11. In a Article，once mentioned of 499-40-1, Quality Control of: (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal
Herein, we report the synthesis, molecular structures and bioevaluation of two different cationic copper(ii) complexes with the third generation quinolone antibacterial agent levofloxacin (lvx) and 2N-substituted ligands 2,2?-dipyridylamine (bipyam) and bathophenanthroline (BPhen). The molecular structures of [Cu(lvx)(bipyam)Cl]+ (1) and [Cu(lvx)(BPhen)Cl]+ (2) exhibit distorted square-pyramidal coordination environments around the copper atoms with tau values of 0.137 in (1) and 0.0316 in (2). Their binding interaction modes towards calf-thymus (CT) DNA were examined by a series of spectroscopy measurements including electronic absorption, viscosity measurements, circular dichroism and fluorescence spectroscopy. Also, the quenching mechanism, thermodynamic parameters (DeltaG, DeltaH and DeltaS) and total number of binding sites per albumin (n) were explored at different temperatures (25, 30 and 35 C) by fluorescence quenching experiments. These complexes quench the intrinsic fluorescence of serum albumins and complex 2 exhibits the highest binding constant values at 25 C (KBSA = 7.77 ± 0.02 × 105 M-1 in the case of bovine serum albumin (BSA) and KHSA = 1.55 ± 0.01 × 105 M-1 in the case of human serum albumin (HSA)). Molecular docking simulations on the crystal structures of CT DNA, BSA and HSA were employed in order to study the ability of the complexes to bind to these target macromolecules. The in vitro bio-efficacies of the complexes were screened against nine different microorganisms to examine their antibacterial potential. Furthermore, the complexes were also subjected to cytotoxicity tests against the MCF-7 cancer cell line and the results indicated that both complexes have superior cytotoxicity to the currently used chemotherapeutic agent cisplatin.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 499-40-1 is helpful to your research., Quality Control of: (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal
Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics