65412-03-5, Name is 4-(2-Aminoethyl)tetrahydro-2H-pyran, molecular formula is C7H15NO, belongs to tetrahydropyrans compound, is a common compound. In a patnet, once mentioned the new application about 65412-03-5, Product Details of 65412-03-5
A wide variety of 2-substituted aminoadenosines were prepared for comparison with the moderately A2 receptor selective adenosine agonist 2-anilinoadenosine (CV-1808).High selectivity combined with significant affinity at the A2 receptor in rat membranes was observed for those amines bearing a two-carbon chain to which was attached an aryl, heteroaryl, or alicyclic moiety. 2-(2-Phenethylamino)adenosine (3d), a 14-fold A2 selective compound, was modified by introduction of a variety of substituents in the benzene ring and the side chain.Some of these changes led to improved A2 affinity and increased selectivity.Replacement of the phenyl moiety by cyclohexenyl produced a 210-fold selective agonist 3ag (CGS 22989) whereas the cyclohexanyl analogue 3af (CGS 22492) was 530-fold selective at the A2 site.These compounds showed hypotensive activity in rat models over a range of doses without the bradycardia observed with less selective agonists.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 65412-03-5. In my other articles, you can also check out more blogs about 65412-03-5
Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics