Top Picks: new discover of Tetrahydro-2H-pyran-3-carboxylic acid

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 873397-34-3 is helpful to your research., Computed Properties of C6H10O3

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.873397-34-3, Name is Tetrahydro-2H-pyran-3-carboxylic acid, molecular formula is C6H10O3. In a Article,once mentioned of 873397-34-3, Computed Properties of C6H10O3

A series of novel beta-hydroxyisovalerylshikonin analogues bearing oxygen-containing substituents at the side-chain hydroxyl of shikonin were designed and synthesized. The cytotoxicities of these compounds were evaluated in vitro against multi-drug resistant (MDR) cell lines DU-145 and HeLa. Most compounds exhibited significant inhibitory activity on both cell lines. The structure-activity relationship showed the analogues with ether substituents displayed the most potent antitumour activity and selective cytotoxicity towards DU-145. Among the compounds with ether substituents, increasing the steric hindrance in the carbon bearing beta-hydroxyl or replace the beta-hydroxyl with acetoxy or methoxy would lead to the decline of cytotoxicity.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 873397-34-3 is helpful to your research., Computed Properties of C6H10O3

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics