Extracurricular laboratory:new discovery of 40191-32-0

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Electric Literature of 40191-32-0. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 40191-32-0, Name is Tetrahydro-2H-pyran-4-carbonyl chloride

A series of 1,2,3,4,6,7,8,12b-octahydropyrazino<2,1-a><2>benzazepine derivatives was prepared and the cestocidal activity of the compounds evaluated in an in vitro Taenia crassiceps screen.Many of these derivatives proved to be highly active, and 2-(cyclohexylcarbonyl)-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazino<2,1-a><2>benzazepine, epsiprantel (BAN) (22), was selected for further development.The structure-activity relationships are discussed.

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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics