Safety of Atorvastatin lactone, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount. 125995-03-1, Name is Atorvastatin lactone, molecular formula is C33H33FN2O4. In a patent, introducing its new discovery.
The invention belongs to the field of pharmaceutical chemistry, provides a 3 – hydroxy – 3 – methyl coenzyme A reductase inhibitors fifth heavenly stem two tai, it is one that contains 3 – fluoro – caprolactone segment and its lactone ring-opening is formed after the 1 – fluoro – 3 – hydroxy valeric acid and its salt or ester multi-substituted pyrimidines he the sandbank contains the fluorine as a modifier, its structural formula as described below: Such compounds tested inhibit HMG – coA reductase activity effect, can be used as a new generation of potential HMG – CoA reductase inhibitor. (by machine translation)
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Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics