Application of 2081-44-9, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.2081-44-9, Name is Tetrahydro-2H-pyran-4-ol, molecular formula is C5H10O2. In a patent, introducing its new discovery.
The present invention relates to the technical field of organic compound synthesis, in particular to a ACC inhibitor and intermediate preparation method. ACC inhibitor intermediates in the preparation method, comprises the following steps: a, compound I halogenated reaction to obtain compound II; b, compound II with the tetrahydropyran – 4 – ol the substitution reaction to obtain compound III; c, compound III in the reducing agent under the action of the reduction reaction to obtain compound IV and ACC inhibitor intermediate V, separation and/or further hydrogenation reduction to obtain ACC inhibitor intermediate V pure product. The reaction of this invention the initial object and the price is low, in order to compound I as the initiator, halo, substituted, reduction, hydrogenation reaction to prepare the intermediates, each step mild reaction conditions, high yield, is suitable for industrial production. (by machine translation)
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Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics