Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In homogeneous catalysis, catalysts are in the same phase as the reactants.10034-20-5, C14H22ClNO9. A document type is Article, introducing its new discovery., HPLC of Formula: C14H22ClNO9
N-peptidyl derivatives of D-glucosamine 7c-7n were synthesized and tested as reversible, substrate analog inhibitors of cysteine and serine-proteases.D-glucosamine itself showed fair inhibiting properties against cysteine-proteases.Derivatives 7c-7i, designed to improve binding at papain active site, displayed reversible inhibition with Ki ranging from 67-860 muM for papain and from 111-2400 muM for cathepsin B.Representative serine proteases were unaffected.No inhibitory activity against human leukocyte elastase was observed for derivatives 7m and 7n bearing veryeffective peptidyl recognizing units for this enzyme. enzyme inhibiting activity / cysteine-protease / serine-protease / D-glucosamine
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Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics