29943-42-8, Dihydro-2H-pyran-4(3H)-one is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a mixture of NaH(1.97 g, 44.96 mmol) in THF(100 ml) was added dropwise dihydro-2H-pyran-4(3H)-one(3 g, 29.96 mmol) in an ice bath. After stirring for 20 mi dimethyl carbonate(3.8 ml, 44.96 mmol) was added. The reaction mixture was stilTed at ft for 3 h. To a mixture of diethyl ether / iN HC1 was poured reaction mixture with stirring. The organic layer was separated, dried over Na2SO4, concentrated under reduced pressure and the residue was purified by column chromatography to afford the desired product 1-1(1.5 g) as a yellow liquid.1H NMR (300 MHz, CDC13) 5 11.752 (s, 1H), 4.267 (m, 2H), 3.863 (m, 2H), 3.783 (m, 2H), 3.758 (s, 3H), 2.393 (m, 2H), 1.85 1 (m, 2H).
29943-42-8, The synthetic route of 29943-42-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ST PHARM CO., LTD.; KIM, Kyungjin; KIM, Uk-Il; YOON, Ji Hye; (32 pag.)WO2017/99424; (2017); A1;,
Tetrahydropyran – Wikipedia
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