33821-94-2, 2-(3-Bromopropoxy)tetrahydro-2H-pyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a mixture of 4-iodo-1H-pyrazole (2.0 g, 10.3 mmol) and Cs CO(5.04 g, 15.5 mmol) in MeCN (28 mL) was added 2-(3-bromopropoxy)tetrahydro-2H-pyran ( 1.84 mL, 10.8 mmol) and the mixturestirred at T overnight. The crude reaction mixture was poured into water andextracted with EtOAc (x 3). The combined organic layers were washed withbrine, dried (MgSO4) and concentrated in vacuo. The resulting residue waspurified by FCC, using a gradient of 0-80% EtOAc in cyclohexane, to give thetitle compound (2.95 g, 81%)., 33821-94-2
The synthetic route of 33821-94-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; CHIESI FARMACEUTICI S.P.A.; Alcaraz, Lilian; Panchal, Terry Aaron; Jennings, Andrew Stephen Robert; Cridland, Andrew Peter; Hurley, Christopher; (80 pag.)KR2016/16973; (2016); A;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics