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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 61363-56-2, Name is 2H-Pyran-3,5(4H,6H)-dione, molecular formula is C5H6O3. In a Patent,once mentioned of 61363-56-2, Electric Literature of 61363-56-2

Substituted furanopyrimidine chemical entities of Formula (I): wherein Ra has any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive therapies; modulating and treating disorders mediated by PDE1 activity or dopaminergic signaling; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training protocols; and treating peripheral disorders, including cardiovascular, renal, hematological, gastroenterological, liver, cancer, fertility, and metabolic disorders.

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In classical electrochemical theory, both the electron transfer rate and the adsorption of reactants at the electrode control the electrochemical reaction 61363-56-2, Name is 2H-Pyran-3,5(4H,6H)-dione, molecular formula is C5H6O3. In a Patent,once mentioned of 61363-56-2, SDS of cas: 61363-56-2

A series of thieno[2,3-6]pyridine derivatives, attached at the 2-position to a substituted anilino moiety, which are substituted in the 3-position by a carbonyl group linked to a pyrrolidin-1-yl ring which in turn forms part of a heteroatom-containing fused bicyclic ring system, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions.

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The present invention is a compound of formula 1wherein R1 is halogen or lower alkyl; R2 is hydrogen, lower alkyl, cycloalkyl, ?(CH2)m-phenyl, wherein the phenyl ring may be substituted by lower alkoxy, or is ?(CH2)m-indolyl; R3 is ?C(O)O-lower alkyl, ?C(O)OH, or a five membered heteroaromatic group, which rings may be substituted by lower alkyl or cycloalkyl; n is 0, 1 or 2; m is 0, 1 or 2; or a pharmaceutically acceptable acid addition salt thereof. Compound I shows high affinity and selectivity for GALA A alpha5 receptor binding sites.

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Effective preparation of cycloheptimidazol-4-ones was developed. The reactions of 2-tosyloxytropone (5) with amidines (6) carried out under simple conditions such as aq. NaOH in toluene at 35C afforded the corresponding cycloheptimidazol-4-ones (3) in low yield. However, by adding tetra-n-butylammonium bromide (n-Bu4NBr) to this reaction system, the yield was improved dramatically. The reaction conditions were screened in detail.

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Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 2H-Pyran-3,5(4H,6H)-dione, you can also check out more blogs about61363-56-2

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 61363-56-2, Name is 2H-Pyran-3,5(4H,6H)-dione, molecular formula is C5H6O3. In a Article,once mentioned of 61363-56-2, Application In Synthesis of 2H-Pyran-3,5(4H,6H)-dione

A copper-catalyzed sequential arylation and intramolecular annulation of 2-(2-bromophenyl)-2,3-dihydroquinazolin-4(1H)-ones with alkyl amidines has been developed for the synthesis of 6-alkyl 11bH-quinazolino[3,4-a]quinazolin-13(12H) -ones (3) in moderate to good yields. However, the arylated products N-(2-(4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)phenyl)benzimidamides (4) are isolated when aryl amidines are used in the transformation.

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A catalyst don`t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. category: Tetrahydropyranscategory: Tetrahydropyrans, , Name is 2H-Pyran-3,5(4H,6H)-dione, molecular formula is C5H6O3. In a patent, introducing its new discovery.

The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORgamma and the treatment of diseases related to the modulation of RORgamma. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.

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Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In homogeneous catalysis, catalysts are in the same phase as the reactants.61363-56-2, C5H6O3. A document type is Patent, introducing its new discovery., Related Products of 61363-56-2

The invention discloses a metal iridium complex and includes the iridium complex of the organic electroluminescent device, the iridium complex of the formula I shown in the general structure formula. The invention of the iridium complex electroluminescent is green to red, high luminous efficiency, at the same time good thermal stability of the material, the material is easy preparation, is easy to be purified, is used as an organic electroluminescent device is the ideal choice of the luminescent material. (by machine translation)

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Herein is disclosed amino-pyrimidine derivatives, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions. The derivatives are useful for increasing cardiac contractility in a mammal.

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A series of polysubstituted pyrimidines were synthesized from in situ generated alpha,beta-unsaturated imines and the corresponding amidine or guanidine derivatives in a convenient one-pot procedure.

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A series of pyrido<2,3-d>pyrimidine angiotensin II (A II) antagonists was synthesized and tested for antagonism of A II. Compounds with a biphenyltetrazole pharmacophore and small alkyl groups at the 2- and 4-positions of the pyridopyrimidine ring were found to be the most potent in an AT1 receptor binding assay and in blocking the A II pressor response in anesthetized, ganglion-blocked A II-infused rats. 5,8-Dihydro-2,4-dimethyl-8-<(2'-(1H-tetrazol-5-yl)<1,1'-biphenyl>-4-yl)methyl>pyrido<2,3-d>pyrimidin-7(6H)-one (4a) was one of the more potent compounds in the binding assay and was the most efficacious compound in the A II-infused rat model. Further study of 4a in Goldblatt (2K-1C) rats showed the compound to have oral bioavailability and to be an efficacious and potent compound in a high renin form of hypertension.

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