850429-50-4,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.850429-50-4,2-(Tetrahydro-2H-pyran-4-yl)acetonitrile,as a common compound, the synthetic route is as follows.
(Tetrahydro-4-pyranyl) -acetonitrile (75 g, 0.60 mol), Pd / C 2.5 g, 400 ml of ethanol was added to a hydrogenation vessel,Replacement 3 times,Hydrogenation,Keep the pressure IMPa,Temperature 25 C,Stirring reaction 12h,The reaction was filtered and the filtrate was transferred to the reactionAnd distilled under reduced pressure to give 65.8 g (0.5 lmo 1) of 4- (2-aminoethyl) tetrahydropyran oil.
The synthetic route of 850429-50-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Shandong Chuancheng Pharmaceutical Co., Ltd.; Liu, Huaizhen; Han, Lixia; Bai, Tiankai; Guo, Ming; Ma, Juliang; (7 pag.)CN106083787; (2016); A;,
Tetrahydropyran – Wikipedia
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